Your doctor should tell you how to treat low blood sugar. Common, less than 1 in 10 but more than 1 in patients experienced: dizziness, headache, reduced appetite, weight decreased, feeling jittery, pain in the stomach area, bloating, indigestion, increased sweating, loss of energy and strength or heartburn, injection site reactions redness. In addition some other side effects have been reported: angiodema, hypersensitivity rashes, itching and rapid swelling of the tissues of the neck, face, mouth or throat , decrease in kidney function, dehydration, sometimes with a decrease in kidney function, unusual taste in the mouth, drowsiness, constipation, burping, flatulence, hair loss rarely.
Changes in INR measurement of blood thinning have been reported when used together with warfarin. Pancreatitis can be a serious, potentially life-threatening medical condition. Take care if you lose weight too quickly as this may not be good for you for example, it can cause dehydration, dizziness upon standing, and gallstones. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Replace the cap on the pen in order to protect from light. Do not freeze. Medicines should not be disposed of via waste water or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
The active substance is exenatide. Each millilitre ml of the solution for injection contains 0. When the pen is empty, you cannot use it again. Each pen has 60 doses to provide 30 days of twice? It is available in pack sizes of 1 and 3 pens. Not all pack sizes may be marketed.
For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder:. Tel Malta Charles de Giorgio Ltd. Tel Tel 30 60 25 S Tlf 47 22 88 18 H Tel 1 France Lilly France S. Tel 40 21 Ireland Eli Lilly and Co. Tel 01 00 Italia Eli Lilly Italia S. Failure to follow these instructions completely may result in a wrong dose, a broken pen or an infection. You do not have to measure any doses, the pen measures each dose for you.
If any part of your pen appears broken or damaged, do not use the pen. This pen is not recommended for use by people who are blind or who cannot see well enough. Help will be needed by a person trained to use the pen.
Healthcare professionals or other caregivers should follow local or institutional policies regarding needle handling. Follow the instructions for hygienic injection technique recommended by your healthcare professional. Follow Section 2 only to set up a new pen before first use. Section 3 of this manual should be used for every injection.
The following are examples of disposable needles that can be used with your BYETTA pen: 29 thin , 30 or 31 thinner gauge diameter 0. Ask your healthcare professional which needle gauge and length is best for you.
Do I use a new needle for each injection? Do not reuse needles. Remove the needle immediately after each injection. This will help prevent leakage of BYETTA, keep out air bubbles, reduce needle clogs, and decrease the risk of infection.
Never push the injection button on the pen unless a needle is attached. How do I throw away my needles? Throw away used needles in a puncture-resistant container or as recommended by your healthcare professional. Do not throw away the pen with a needle attached. Do not share your pen or needles.
Keep your pen and needles out of the reach and sight of children. If needed, wipe the outside of the pen with a clean, damp cloth. White particles may appear on the outside tip of the cartridge during normal use.
You may remove them with an alcohol wipe or alcohol swab. For additional information, contact your healthcare professional. Section 2. Set up your new pen just before you use it for the first time. Follow the New Pen Setup only once. For routine use, do not repeat the New Pen Setup. Pull off the blue pen cap. The liquid should be clear, colourless, and free of particles. If it is not, do not use. Note : A small air bubble in the cartridge is normal.
Remove paper tab from outer needle shield. Push outer needle shield containing the needle straight onto the pen, then screw needle on until secure. Pull off outer needle shield. Do not throw away. The outer needle shield will be used when you are removing the needle from the pen after the injection. Pull off inner needle shield and throw away. A small drop of liquid may appear. Symptoms of a severe allergic reaction can include:.
Call your doctor right away if you have a severe allergic reaction to Byetta. However, mild and severe allergic reactions have been reported since the drug came on the market in This is called hypoglycemia. Talk to your doctor about what to do if you experience symptoms of hypoglycemia, which can include:. Pancreatitis was not reported in clinical studies of Byetta.
However, a few people using Byetta have experienced acute pancreatitis inflammation of the pancreas since the drug came on the market in Some of these cases were serious or fatal. Call your doctor right away if you experience any symptoms of acute pancreatitis. Your doctor may tell you to stop using Byetta. Symptoms of acute pancreatitis can include:.
The weight loss side effect can be beneficial for people with type 2 diabetes. Weight loss is most likely caused by Byetta making you want to eat less. However, Byetta is not a weight loss drug and should not be used solely for this purpose. Weight gain was not reported with Byetta in these studies. Some people using Byetta experience diarrhea. If you get diarrhea while using Byetta, talk with your doctor or pharmacist about how to manage it.
Drink plenty of fluids to avoid getting dehydrated when your body loses more fluid than you drink. You may find that you feel nauseated when you first start using Byetta. Feelings of nausea tend to get better with time. Hair loss alopecia was not reported in clinical studies of Byetta. However, it has been reported by some people using Byetta since the drug was approved. A literature review of safety issues with Byetta and other drugs in the same class did not find any association between pancreatic cancer and use of these drugs.
However, the long-acting form of exenatide, which is the main drug in Byetta, does have such a warning. This form of exenatide is available as the brand-name drug Bydureon. An FDA boxed warning is used to alert doctors and patients about potentially serious side effects that might be associated with a drug.
Bydureon has one because it was shown to cause thyroid cancer in some animals. However, results from animal studies do not necessarily apply to humans. The FDA has also issued boxed warnings about thyroid cancer for other medications in the same drug class as Byetta. These drugs are liraglutide Victoza , semaglutide Ozempic , albiglutide Tanzeum , and dulaglutide Trulicity. These warnings are also based on animal studies. However, these drugs have not been shown to cause thyroid cancer in humans.
This is because data needs to be collected over a very long period of time. As with all medications, the cost of Byetta can vary. To find current prices for Byetta in your area, check out GoodRx. The cost you find on GoodRx. If you need financial support to pay for Byetta, or if you need help understanding your insurance coverage, help is available. AstraZeneca, the manufacturer of Byetta, offers a savings card called MySavingsRx, which can help lower the cost of Byetta.
To learn more, call or visit the program website. Other drugs are available for treating type 2 diabetes. Some may be a better fit for you than others. They can tell you about other medications that may work well for you. You may wonder how Byetta compares to other medications that are prescribed for similar uses. Here we look at how Byetta and Bydureon are alike and different. Byetta and Bydureon are both FDA-approved to help control blood sugar levels in adults with type 2 diabetes.
They are used along with a diet and exercise program. Both of these medications contain exenatide, so they work the same way in the body. Byetta is a short-acting form of the drug that wears off after a few hours. Bydureon is a long-acting form of exenatide that works for a longer period.
Byetta comes as a prefilled multidose injection pen. You give yourself an injection under your skin subcutaneous twice a day, before your main meals. Bydureon comes as a single-dose injection pen or a single-dose syringe. It also comes as a single-dose prefilled autoinjector called Bydureon BCise.
With all forms of Bydureon, you give yourself an injection under your skin once a week, on the same day each week. Byetta and Bydureon both contain exenatide. Therefore, both medications can cause very similar side effects. Below are examples of these side effects. These lists contain examples of more common side effects that can occur with Byetta, with Bydureon, or with both drugs when taken individually.
These lists contain examples of serious side effects that occur with Bydureon, and both Bydureon and Byetta when taken individually.
A boxed warning is the strongest warning the FDA requires. It alerts doctors and patients about drug effects that may be dangerous. Byetta and Bydureon have been directly compared in a clinical study. In this study, the effectiveness of the drugs was compared when they were both used on their own and when they were used in combination with other diabetes drugs.
The study found that on average, Bydureon lowered hemoglobin by 0. Over the same time period, people treated with Bydureon had an average weight loss of 5 lb. People treated with Byetta lost an average of 3 lb. Byetta and Bydureon are both brand-name drugs.
There are currently no generic forms of either drug. Brand-name medications usually cost more than generics. According to estimates on GoodRx. Byetta and Victoza are prescribed for similar uses. Below are details of how these medications are alike and different. Byetta and Victoza are both FDA-approved to help control blood sugar levels in adults with type 2 diabetes.
They are both used along with a diet and exercise program. Victoza is also FDA-approved to reduce the risk of heart attacks and strokes in people with type 2 diabetes who have heart disease. Byetta contains exenatide, and Victoza contains liraglutide.
These medications are from the same drug class, so they work in the same way in the body. With Byetta, you give yourself an injection under your skin subcutaneous twice a day, before your main meals.
With Victoza, you give yourself an injection under your skin once a day, at any time of day. Byetta and Victoza contain drugs from the same class. These lists contain examples of more common side effects that can occur with Byetta, with Victoza, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Victoza, and with both Byetta and Victoza when taken individually.
Byetta and Victoza have been directly compared in a clinical study. In this study, the effectiveness of the drugs was compared when they were both used in combination with other drugs to treat diabetes metformin , a sulfonylurea, or both.
The study found that, on average, Victoza lowered hemoglobin A1c HbA1c by 0. Over the same period, people treated with Victoza and people treated with Byetta both lost an average of 6. Byetta and Victoza are both brand-name drugs. Byetta may also be used off-label for other conditions. Byetta is FDA-approved to help control blood sugar levels in adults with type 2 diabetes. This leads to high blood sugar levels. Byetta reduces hemoglobin A1c HbA1c , which is a measure of your average blood sugar levels over 3 months.
Byetta helps lower your blood sugar after eating a meal. It also lowers your blood sugar between meals. This is called your fasting blood sugar level. Byetta can also help some people lose weight. Byetta may be used on its own or with other diabetes medications.
These other medications include metformin , glipizide, and pioglitazone. In a clinical study of people using Byetta on its own:. When used with another diabetes drug, Byetta is most often used with metformin. In a clinical study of people treated with Byetta and metformin:. Exenatide belongs to a group of medications known as glucagon-like peptide-1 GLP-1 receptor agonists. It is used along with other medications e.
It works by helping your body make more insulin and control blood glucose levels. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
Non-medicinal ingredients: m-cresol 2. Available as prefilled pens: 1. Inject this medication within 60 minutes before the morning and evening meal.
You can also inject this medication before the 2 main meals of the day as long as they are at least 6 hours apart. Do not inject this medication after a meal. This medication is clear and colourless and should not contain particles. Do not use it if the solution appears cloudy or coloured. This medication is available as a prefilled pen for injection. Read the user manual for instructions on how to properly use this medication. If you are not sure how to use this medication, contact your doctor or pharmacist.
If you are taking a sulfonylurea e. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications.
If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor. It is important that this medication be used exactly as prescribed by your doctor.
If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Before first use , store this medication in the refrigerator, protect it from light, and keep it out of the reach of children.
Do not allow it to freeze. After the first use , store this medication at room temperature. Discard any unused medication that is still in the pen 30 days after first use. Do not store this medication with the needle attached as this may cause the medication to leak. Do not dispose of medications in wastewater e.
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